Bioprinting offers the opportunity to develop more complex standardized skin models.


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The field of skin substitutes has received growing attention over the last 5-8 years. In particular, since animal testing was banned for cosmetic products in developed countries.

The skin is complex, containing more than ten cell components. Therefore, researchers need to develop 3D models as sophisticated as possible. At a symposium of the European Centre for Dermocosmetology, Dr Sandrine Héraud R&D Project Manager at LabSkin Creation and her team introduced a skin model that reproduces the skin condition atopic dermatitis.

Atopic dermatitis is a chronic inflammatory disease which affects more than one infant out of ten. Dr Héraud’s team have developed an innovative model involving the use of lymphocytes and cells derived from patients with atopic dermatitis. It is the first human in vitro model of atopic dermatitis with an immunity component.

The newly introduced skin model is generated through bioprinting which offers the advantage of creating highly complex 3D structures, offering a more accurate and standardized skin model. Dr Héraud seems very optimistic about the results. “We can get a mature skin sample in 21 days, compared to 45 with an in vitro culture”- she said.

 

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