Enjoy the benefits of flexibility, easy handling, and synthetic features
Our hydrogels provide synthetic yet biologically-relevant alternatives to animal-derived 3D matrices such as Matrigel and collagen.
Our Synthetic gels Provide Flexibility
Biogelx technology is based on a two peptide system: a hydrophobic ‘gelator’ peptide, and a hydrophilic ‘surfactant’ peptide. They self-assemble and form fibres in aqueous environments. The fibres present hydrophilic functionality on the surface (‘core-shell’ assembly), thereby presenting a suitable surface chemistry for cell adhesion. The chemical environment provided by our hydrogels can be tuned, providing additional opportunities to optimize the matrix environment to specific cell types. The “surfactant” functionality of the peptide fibres can be altered by incorporating alternative amino acid residues such as lysine. Also available are hydrogels which incorporate biomimetic peptide sequences of key extracellular matrix proteins such as fibronectin, laminin, and collagen. The ability to incorporate such functionality allows Biogelx hydrogels provide synthetic yet biologically-relevant alternatives to animal-derived 3D matrices such as Matrigel and collagen.
Our Bio-inspired gels are easy to handle
Allowing the tuning of final gel stiffness, the powder form allows easy incorporation of application-specific proteins, growth factors, or other bioactive molecules e.g. drug molecules. The gelation process is triggered in a controlled manner, with no pH or temperature requirements. As such, the materials are amenable to a huge variety of handling techniques, for example, they can be used in standard 2D/3D well plate formats (384 – 6 well), are compatible with automated liquid handling systems and are injectable.